Alterations in skeletal muscle health and biomechanical properties in patients with early rheumatoid arthritis: an exploratory cross-sectional study
In this exploratory study, patients with early RA exhibited multiple skeletal muscle deficits across clinical, physiologic, and biomechanical domains compared to controls with similar muscle mass and physical activity. <i>In vivo</i> and <i>in vitro</i> skeletal muscle biomechanical assessments may be useful to identify these deficits to better understand and improve RA muscle health.
Authors
- William E. Kraus (ORCID: https://orcid.org/0000-0003-1930-9684)
- Johanna L. Johnson (ORCID: https://orcid.org/0000-0001-9766-1814)
- George A. Truskey (ORCID: https://orcid.org/0000-0002-6885-4489)
- Brian J. Andonian (ORCID: https://orcid.org/0000-0003-1847-0660)
- Kim M. Huffman (ORCID: https://orcid.org/0000-0003-4708-4734)
- Alyssa M Sudnick
- Mingzhi Xu (ORCID: https://orcid.org/0009-0006-9626-1169)
- Hailee Patel
Institutions
- Duke University (US)
- Texas A&M University (US)
Publication Details
- Journal
- Frontiers in Physiology
- Published
- 2025-04-23
- DOI
- https://doi.org/10.3389/fphys.2025.1575689
- Primary Topic
- Rheumatoid Arthritis Research and Therapies
- Type
- article
- Field-Weighted Citation Impact
- 0.00