LL37 promotes angiogenesis: a potential therapeutic strategy for lower limb ischemic diseases
LL37 promotes angiogenesis via the VEGFA-PI3K/AKT/mTOR pathway, showing potential for treating lower limb ischemia by improving perfusion.
Authors
- Qiancheng Mao
- Gang Wu (ORCID: https://orcid.org/0000-0003-0359-103X)
- Dongxu Zhang (ORCID: https://orcid.org/0000-0002-9186-4052)
- Yingying Yang (ORCID: https://orcid.org/0000-0001-6779-080X)
- Jitao Wu (ORCID: https://orcid.org/0000-0002-6243-5152)
- Yini Wang (ORCID: https://orcid.org/0000-0002-1154-6733)
Institutions
- Yuhuangding Hospital (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2025-04-23
- DOI
- https://doi.org/10.3389/fphar.2025.1587351
- Citations
- 4
- Primary Topic
- Angiogenesis and VEGF in Cancer
- Type
- article
- Field-Weighted Citation Impact
- 3.22
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Shandong Province