Post-exertional malaise in Long COVID: subjective reporting versus objective assessment
Self-report of PEM is common in Long COVID. However, observable PEM following an exercise stressor was not frequent in this small cohort. When present, PEM descriptions during QI were less severe in Long COVID than in ME/CFS. Positive responses after an exercise stressor were common in Long COVID. Exercise testing to determine the presence of PEM may have utility for guiding clinical management of Long COVID.
Authors
- Avindra Nath (ORCID: https://orcid.org/0000-0003-0927-5855)
- Gina Norato (ORCID: https://orcid.org/0000-0003-1324-0217)
- Leighton Chan (ORCID: https://orcid.org/0000-0001-9001-872X)
- Marie Stockman
- Gayle McCrossin (ORCID: https://orcid.org/0000-0002-8612-6995)
- C. Stephenie Vetter (ORCID: https://orcid.org/0000-0002-4694-677X)
- Nicholas Grayson (ORCID: https://orcid.org/0000-0002-9998-6783)
- Brian Walitt (ORCID: https://orcid.org/0000-0003-1743-5230)
- Nathan Camarillo
- Barbara Stussman (ORCID: https://orcid.org/0000-0002-5780-0186)
- Lisa M. K. Chin (ORCID: https://orcid.org/0000-0002-0178-739X)
- Alenka Ferrufino
- Ashade Adedamola
Institutions
- National Institutes of Health (US)
- National Institute of Neurological Disorders and Stroke (US)
- National Institutes of Health Clinical Center (US)
Publication Details
- Journal
- Frontiers in Neurology
- Published
- 2025-04-23
- DOI
- https://doi.org/10.3389/fneur.2025.1534352
- Citations
- 8
- Primary Topic
- Long-Term Effects of COVID-19
- Type
- article
- Field-Weighted Citation Impact
- 11.11
Funders
- National Institutes of Health
- NIH Clinical Center