Quality Assessment and Standardization of Samvardhana Ghrita: A Comprehensive Pharmacognostical, Physico-Chemical, and Chromatographic Evaluation

This study aimed to authenticate and evaluate the quality of Samvardhana Ghrita, an Ayurvedic formulation, by analyzing its ingredients and therapeutic properties as outlined in the Ayurvedic Pharmacopoeia of India (API). Raw materials were sourced from local and specialized markets, and the Ghrita was prepared according to API guidelines. The authenticity of key ingredients such as Bala, Atibala, Khadira, Prishniparni, Tinisha, and Kebuka was confirmed through organoleptic evaluation, physico-chemical analysis, and Thin Layer Chromatography (TLC). Organoleptic assessment revealed the preparation's viscous consistency, algae green color, and bitter taste, typical of herbal formulations. Physico-chemical analysis demonstrated low moisture content (0.12%), an iodine value of 35.69, and a saponification value of 235.79 mg KOH/g, confirming stability and quality. TLC analysis identified five distinct retention factors (Rf values), supporting the presence of multiple bioactive components. These results confirm the authenticity, stability, and therapeutic efficacy of Samvardhana Ghrita, supporting its use for promoting child growth and treating conditions like Pangu, Muka, Ashruti, and Jada, as prescribed by Acharya Kashyapa. The study emphasizes the importance of quality control measures for ensuring the safe and effective clinical application of Ayurvedic formulations. Key words: Ayurveda, Atibala, Bala, Kebuka, Khadira, Physico-chemical analysis, Prishniparni, Samvardhana Ghrita, Tinisha, and Thin Layer Chromatography