Associations of choroid plexus volume with white matter hyperintensity volume and susceptibility and plasma amyloid markers in cerebral small vessel disease
CP volume changes were significantly correlated with both WMH volume and WMH susceptibility in CSVD patients. These findings suggest that CP-mediated pathways may link amyloid metabolism to CSVD progression.
Authors
- Lingfei Guo (ORCID: https://orcid.org/0000-0002-4885-625X)
- Yiwen Chen (ORCID: https://orcid.org/0009-0007-9411-0145)
- Changhu Liang (ORCID: https://orcid.org/0000-0003-3796-2978)
- Yena Che (ORCID: https://orcid.org/0000-0003-4742-4778)
- Zhenyu Cheng (ORCID: https://orcid.org/0000-0002-7240-9126)
- Nan Zhang (ORCID: https://orcid.org/0000-0002-9675-5322)
- Jing Li (ORCID: https://orcid.org/0000-0001-9392-6600)
- Meng Li (ORCID: https://orcid.org/0000-0001-7592-2091)
- Yuanyuan Wang (ORCID: https://orcid.org/0000-0002-6666-0090)
- Pengcheng Liang (ORCID: https://orcid.org/0009-0007-7392-2566)
- Na Wang (ORCID: https://orcid.org/0000-0001-6191-4760)
Institutions
- Shandong University of Aeronautics (CN)
- Shandong Provincial Hospital (CN)
- Jena University Hospital (DE)
- Beijing Tsinghua Chang Gung Hospital (CN)
- Shandong First Medical University (CN)
Publication Details
- Journal
- Alzheimer s Research & Therapy
- Published
- 2025-04-23
- DOI
- https://doi.org/10.1186/s13195-025-01740-8
- Citations
- 7
- Primary Topic
- Alzheimer's disease research and treatments
- Type
- article
- Field-Weighted Citation Impact
- 8.15
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Shandong Province
- Medical and Health Science and Technology Development Project of Shandong Province