Utility of serum cytokine testing to differentiate complicated common variable immunodeficiency in resource limited settings
sIL-2R and IL-10 testing had statistically comparable diagnostic performance for complicated CVID as compared to the current standard-of-care using flow cytometry.
Authors
- Mei‐Sing Ong (ORCID: https://orcid.org/0000-0002-1241-1013)
- Uhuru Kamau
- Joseph Hong
- Karen M. Gilbert (ORCID: https://orcid.org/0000-0002-3297-0250)
- Sara Barmettler (ORCID: https://orcid.org/0000-0001-8188-9187)
- Henry Ssemaganda (ORCID: https://orcid.org/0009-0001-2877-3465)
- Katherine E. Liu
- Jocelyn R. Farmer (ORCID: https://orcid.org/0000-0003-4901-9848)
- Daniel DiGiacomo (ORCID: https://orcid.org/0000-0001-6344-7246)
- Neha V. Khairnar (ORCID: https://orcid.org/0009-0000-9187-6734)
- Andrew Pak
- Aditi Jogdand (ORCID: https://orcid.org/0000-0001-8483-7219)
Institutions
- Lahey Hospital and Medical Center (US)
- Harvard University (US)
- Massachusetts General Hospital (US)
- Lahey Medical Center (US)
- Harvard Pilgrim Health Care (US)
- Jersey Shore University Medical Center (US)
Publication Details
- Journal
- Journal of Allergy and Clinical Immunology Global
- Published
- 2025-04-23
- DOI
- https://doi.org/10.1016/j.jacig.2025.100488
- Citations
- 3
- Primary Topic
- Immunodeficiency and Autoimmune Disorders
- Type
- article
- Field-Weighted Citation Impact
- 2.39
Funders
- American Academy of Allergy, Asthma and Immunology Foundation
- National Institute on Minority Health and Health Disparities
- Division of Microbiology and Infectious Diseases, National Institute of Allergy and Infectious Diseases