Vaccination of people with solid tumors and diabetes: existing evidence and recommendations. A position statement from a multidisciplinary panel of scientific societies
Diabetes and cancer are two of the most common public health concerns worldwide. The complex interplay of these two conditions is a growing area of research, as patients with diabetes are at increased risk for developing cancer, and vice versa. Furthermore, both patient populations show increased risk of many communicable infectious diseases and their adverse consequences, while vaccination can play a crucial role in their prevention, improving patient outcomes. Vaccination should represent a standard part of care for patients with cancer, diabetes, and both the diseases simultaneously, including people undergoing cancer treatment or in remission. Several international guidelines provide recommendations for vaccinating people with cancer or diabetes, but the two conditions have not been specifically evaluated together. Here we present a multidisciplinary consensus position paper on vaccination in patients with cancer and diabetes. The position paper is the result of a collaborative effort between experts from the Italian Association of Medical Oncology (AIOM), Italian Association of Medical Diabetologists (AMD), Italian Society of Diabetology (SID), Italian Society of Endocrinology (SIE), and Italian Society of Pharmacology (SIF). The paper provides a comprehensive overview of the current state-of-the-art knowledge on vaccination in patients with cancer and diabetes. It discusses the importance of vaccination in preventing infections, focuses attention on the need to consider the unique challenges faced by patients with cancer and diabetes when it comes to vaccine administration, and highlights the need for coordinated care to optimize treatment outcomes. Overall, the consensus position paper provides healthcare professionals caring for patients with cancer and diabetes recommendations on the use of various vaccines, including influenza, COVID-19, HZV, and HPV vaccines, as well as guidance on how to address common concerns and challenges related to vaccine administration.
Authors
- Matteo Verzè
- Rossella Mazzilli (ORCID: https://orcid.org/0000-0001-6707-3413)
- Dario Giuffrida (ORCID: https://orcid.org/0000-0001-6404-2304)
- Antongiulio Faggiano (ORCID: https://orcid.org/0000-0002-9324-3946)
- Antonella Argentiero
- Federica Perrone (ORCID: https://orcid.org/0000-0003-4406-8245)
- Gianluca Aimaretti (ORCID: https://orcid.org/0000-0002-6186-0106)
- Annalisa Natalicchio (ORCID: https://orcid.org/0000-0002-6131-7517)
- Stefania Gori (ORCID: https://orcid.org/0000-0001-6320-405X)
- Marco Gallo (ORCID: https://orcid.org/0000-0001-7166-0848)
- Angelo Avogaro (ORCID: https://orcid.org/0000-0002-1177-0516)
- Stella D’Oronzo (ORCID: https://orcid.org/0000-0002-1071-2058)
- Angioletta Lasagna (ORCID: https://orcid.org/0000-0002-9611-1164)
- Nicola Silvestris
- Alberto Ragni (ORCID: https://orcid.org/0000-0001-9278-8939)
- Laura Sciacca (ORCID: https://orcid.org/0000-0002-3258-7200)
- Maria Chiara Zatelli (ORCID: https://orcid.org/0000-0001-8408-7796)
- Matteo Monami (ORCID: https://orcid.org/0000-0001-9349-828X)
- Alessio Cortellini (ORCID: https://orcid.org/0000-0002-1209-5735)
- Francesco Giorgino (ORCID: https://orcid.org/0000-0001-7372-2678)
- Enzo Tuveri
- Stefano Fogli (ORCID: https://orcid.org/0000-0002-7845-2598)
- Valerio Renzelli
- Giampiero Marino
- Francesco Felicetti (ORCID: https://orcid.org/0000-0002-6642-8750)
- Monica Montagnani (ORCID: https://orcid.org/0000-0002-5697-8185)
- Nicola Marrano (ORCID: https://orcid.org/0000-0001-6587-6087)
- Tindara Franchina (ORCID: https://orcid.org/0000-0001-5920-4997)
- Lelio Morviducci
- Riccardo Candido (ORCID: https://orcid.org/0000-0003-2385-9160)
Institutions
- University of Pisa (IT)
- University of Messina (IT)
- Università degli Studi del Piemonte Orientale “Amedeo Avogadro” (IT)
- University of Trieste (IT)
- Università Campus Bio-Medico (IT)
- University of Ferrara (IT)
- Fondazione Roma (IT)
- Hammersmith Hospital (GB)
- University of Catania (IT)
- Azienda Ospedaliera Citta' della Salute e della Scienza di Torino (IT)
- Ospedale Sacro Cuore Don Calabria (IT)
- Ospedale di Santo Spirito (IT)
- Istituto Oncologico Veneto (IT)
- Tumour Institute of Tuscany (IT)
- Istituto Tumori Bari (IT)
- Campus Bio Medico University Hospital (IT)
- Ospedale Generale Regionale Francesco Miulli (IT)
- Policlinico San Matteo Fondazione (IT)
- Azienda Ospedaliera Nazionale SS. Antonio e Biagio e Cesare Arrigo (IT)
- Azienda Sanitaria Locale Roma 3 (IT)
- Nano Carbon (Poland) (PL)
- University of Florence (IT)
- Imperial College London (GB)
- University of Bari Aldo Moro (IT)
- Sapienza University of Rome (IT)
Publication Details
- Journal
- Journal of Endocrinological Investigation
- Published
- 2025-04-23
- DOI
- https://doi.org/10.1007/s40618-025-02586-5
- Citations
- 2
- Primary Topic
- Neutropenia and Cancer Infections
- Type
- article
- Field-Weighted Citation Impact
- 2.09
Funders
- Università degli Studi di Ferrara