The Role of Bacterial Protease Enzymes and In Silico Prediction on the Effectiveness of Medical Applications

Bacterial protease enzymes have a wide range of medical applications, particularly in the treatment of infected wounds and therapy for protein digestion disorders. Proteases produced by bacteria such as Bacillus pseudomycoides show great potential for medical therapy due to their ability to break down proteins in the human body. In silico prediction using bioinformatics software such as AutoDock and PyMOL allows researchers to analyze the three-dimensional structure and molecular interactions of proteases with target substrates before conducting laboratory experiments. This article examines the role of bacterial protease enzymes in medical applications and the benefits of using in silico prediction to study the therapeutic potential of proteases. With a combined approach of experimentation and in silico analysis, the process of developing protease-based therapies can be more efficient and faster. This study emphasizes the importance of bioinformatics approaches in accelerating the discovery of enzyme-based medical therapies for future clinical applications.

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Publication Details

Journal
Dinasti Health and Pharmacy Science
Published
2025-04-22
DOI
https://doi.org/10.38035/dhps.v2i4.1841
Primary Topic
Enzyme Production and Characterization
Type
article
Field-Weighted Citation Impact
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article

The Role of Bacterial Protease Enzymes and In Silico Prediction on the Effectiveness of Medical Applications

Salsabila Dwi Fitri, Yorasakhi Ananta, Adi Muliawan
Dinasti Health and Pharmacy Science
Enzyme Production and Characterization
article

The Role of Bacterial Protease Enzymes and In Silico Prediction on the Effectiveness of Medical Applications

Salsabila Dwi Fitri, Yorasakhi Ananta, Adi Muliawan
article en

Abstract

Bacterial protease enzymes have a wide range of medical applications, particularly in the treatment of infected wounds and therapy for protein digestion disorders. Proteases produced by bacteria such as Bacillus pseudomycoides show great potential for medical therapy due to their ability to break down proteins in the human body. In silico prediction using bioinformatics software such as AutoDock and PyMOL allows researchers to analyze the three-dimensional structure and molecular interactions of proteases with target substrates before conducting laboratory experiments. This article examines the role of bacterial protease enzymes in medical applications and the benefits of using in silico prediction to study the therapeutic potential of proteases. With a combined approach of experimentation and in silico analysis, the process of developing protease-based therapies can be more efficient and faster. This study emphasizes the importance of bioinformatics approaches in accelerating the discovery of enzyme-based medical therapies for future clinical applications.

Dinasti Health and Pharmacy ScienceVol. 2(4)
Universitas Jambi (ID), Mercu Buana University (ID), Andalas University (ID)
Openalex Percentile: Top 90%
Enzyme Production and Characterization
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