Multiomics from Alzheimer’s Brains and Mesenchymal Stem Cell-Derived Extracellular Vesicles Identifies Therapeutic Potential of Specific Subpopulations to Target Mitochondrial Proteostasis
This study underscores the critical role of proteomic alterations in AD and identifies a promising EV subpopulation, enriched with proteins targeting mitochondrial proteostasis, as a potential therapeutic strategy for AD.
Authors
- Morteza Abyadeh (ORCID: https://orcid.org/0000-0003-4513-7142)
- Alaattin Kaya (ORCID: https://orcid.org/0000-0002-6132-5197)
Institutions
- Virginia Commonwealth University (US)
- University of Virginia (US)
Publication Details
- Journal
- Journal of Central Nervous System Disease
- Published
- 2025-04-23
- DOI
- https://doi.org/10.1177/11795735251336302
- Citations
- 1
- Primary Topic
- Extracellular vesicles in disease
- Type
- article
- Field-Weighted Citation Impact
- 0.81
Funders
- National Institute on Aging