Correlation between a few hematological variables and D-Dimer in non-vaccinated individuals and individuals who received Pfizer vaccine

Background and objective: When a blood clot forms in an artery or a vein, it is called thrombosis. Thus, D-dimer can be thought of as a biomarker of activation of coagulation and fibrinolysis, and it is frequently used to rule out venous thromboembolism (VTE). This study was conducted to find out the relationship between RBC, WBC, Hb, platelets with the thrombotic variable, which is represented by D-dimer and impact of Pfizer vaccine on these variables. Methods: Forty male and female patients aged 40 – 65 years with complete data records were included in this analysis for evaluation the correlations among RBC, Hb, WBC, platelets, and d-dimer. Ten students (male and females) aged 19-22 years and 10 old subjects aged 44-73 years were used for estimation the effect of the Pfizer vaccination on previous parameters. Results: The results of this study showed that there is no correlation between all these measures and the D-dimer. Only there was a positive correlation between RBC and Hb, and between WBC and Hb. In addition, there was an increase in WBC, platelets and D-Dimer after one week of receiving the Pfizer vaccine in young and old groups. Conclusion: There is no correlation between a rise or a decrease in the counts or levels of hematological measures (RBC, WBC, Hb, platelets) with the occurrence of thrombosis. The study also revealed that the Pfizer vaccine had an elevated effect on the WBC, platelets, and d-dimer measurements after one week. Keywords: D-Dimer; Pfizer; RBC; WBC; WBC; Platelets.