Safety and efficacy of immune checkpoint inhibitors in cancer patients with pre-existing autoimmune disease

Objective response rate 33% (23%-44%) 29% (19%-41%) RR 1.21 (0.88-1.86) 24% (11%-40%) 19% (11%-30%) RR 1.56 (1.19-2.04)ICI discontinuation 15% (10%-20%) 5% (2%-9%) RR 1.61 (1.12-2.31)10% (5%-14%) 3% (0%-8%) RR 2.22 (0.77-6.41)

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Publication Details

Journal
Journal of Cancer Biology
Published
2025-04-23
DOI
https://doi.org/10.46439/cancerbiology.6.068
Primary Topic
Cancer Immunotherapy and Biomarkers
Type
article
Field-Weighted Citation Impact
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article

Safety and efficacy of immune checkpoint inhibitors in cancer patients with pre-existing autoimmune disease

Nagashree Seetharamu, Margaret Locke, Adit Singhal, Wint Yan Aung
Journal of Cancer Biology
Cancer Immunotherapy and Biomarkers
article

Safety and efficacy of immune checkpoint inhibitors in cancer patients with pre-existing autoimmune disease

Nagashree Seetharamu, Margaret Locke, Adit Singhal, Wint Yan Aung
article en

Abstract

Objective response rate 33% (23%-44%) 29% (19%-41%) RR 1.21 (0.88-1.86) 24% (11%-40%) 19% (11%-30%) RR 1.56 (1.19-2.04)ICI discontinuation 15% (10%-20%) 5% (2%-9%) RR 1.61 (1.12-2.31)10% (5%-14%) 3% (0%-8%) RR 2.22 (0.77-6.41)

Journal of Cancer BiologyVol. 6(1)
Northwell Health (US)
Good health and well-being
Openalex Percentile: Top 87%
Cancer Immunotherapy and Biomarkers
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