Association Between Body Iron Status and Biological Aging

The positive association with ferritin is consistent with the proposed role of oxidative stress in accelerated aging associated with high iron exposure. However, the observed inverse associations with serum iron and transferrin saturation are not consistent with this common explanation, and future studies are needed to examine potential explanations.

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Publication Details

Journal
Nutrients
Published
2025-04-23
DOI
https://doi.org/10.3390/nu17091409
Primary Topic
Iron Metabolism and Disorders
Type
article
Field-Weighted Citation Impact
0.00

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article

Association Between Body Iron Status and Biological Aging

Jack A. Taylor, Mary V. Díaz-Santana, Ann Von Holle, Dale P. Sandler et al.
Nutrients
Iron Metabolism and Disorders
article

Association Between Body Iron Status and Biological Aging

Jack A. Taylor, Mary V. Díaz-Santana, Ann Von Holle, Dale P. Sandler, Jacob K. Kresovich, Zongli Xu, Katie M. O’Brien, Clarice Ring Weinberg, Sahana Ramamurthy
article en

Abstract

The positive association with ferritin is consistent with the proposed role of oxidative stress in accelerated aging associated with high iron exposure. However, the observed inverse associations with serum iron and transferrin saturation are not consistent with this common explanation, and future studies are needed to examine potential explanations.

NutrientsVol. 17(9)
North Carolina State University (US), Moffitt Cancer Center (US), National Institute of Environmental Health Sciences (US)
National Institute of Environmental Health Sciences
Good health and well-being
Openalex Percentile: Top 89%
Iron Metabolism and Disorders
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