Association of albumin-bilirubin grade with short- and long-term mortality in patients with heart failure: a cohort study using restricted cubic splines and propensity score matching
RCS analyses revealed a nonlinear relationship between ALBI grade and 30-, 90-, and 360-day mortality in patients with HF, with a threshold value identified at -1.92. When ALBI scores were below - 1.92, the risk of mortality in HF patients remained relatively stable. In contrast, as ALBI scores approached and exceeded - 1.92, the mortality risk increased rapidly. Before PSM, both ALBI grades 2 and 3 were independent predictors of mortality in patients with HF; however, after PSM, ALBI grade 2 was not statistically associated with patient mortality. This result was supported by Kaplan-Meier (K-M) analysis.
Authors
- Hongkai Dai
- Xiaoyan Yuan (ORCID: https://orcid.org/0000-0002-7210-2407)
- Jinlong Luo (ORCID: https://orcid.org/0000-0001-9878-4832)
- Y. J. Cu
- Xi Gao (ORCID: https://orcid.org/0000-0003-0990-3452)
- Yurou Wang (ORCID: https://orcid.org/0000-0002-2176-2069)
- Chengye Zhan
- Cheng Li (ORCID: https://orcid.org/0009-0006-9374-5707)
- Yingfang Zheng
Institutions
- Tongji Hospital (CN)
- Huazhong University of Science and Technology (CN)
Publication Details
- Journal
- BMC Cardiovascular Disorders
- Published
- 2025-04-23
- DOI
- https://doi.org/10.1186/s12872-025-04760-2
- Citations
- 3
- Primary Topic
- Advanced Causal Inference Techniques
- Type
- article
- Field-Weighted Citation Impact
- 7.89