Caudate Head Ischemic Stroke with Concurrent Tubercular Meningoencephalitis: A Case Report

<b>Background and Clinical Significance</b>: The pathogenesis of ischemic lesions in tubercular meningoencephalitis remains unclear, as do the best therapeutic strategies during the acute phase and for secondary prevention. <b>Case Presentation</b>: We report on an atypical case of tubercular meningoencephalitis with a concomitant ischemic stroke. The infectious origin of the ischemic lesion was hypothesized due to a discrepancy between clinical and radiological findings. The patient underwent neuroimaging, blood tests, and a lumbar puncture to diagnose tubercular meningoencephalitis. She subsequently started on antitubercular therapy. Despite the initiation of treatment, her neurological condition worsened. A computed tomography revealed hydrocephalus, leading to the placement of an external ventricular shunt. This intervention resulted in a reduction in ventricular size and an overall improvement in her clinical condition. To reduce the risk of death, secondary prophylaxis with cardioaspirin was added to her treatment regimen. <b>Conclusions</b>: This report highlights the diagnostic and therapeutic challenges encountered in managing patients with tubercular meningitis presenting with concomitant ischemic stroke. By elucidating the complexities of this clinical scenario, we emphasize the importance of early recognition, comprehensive evaluation, and multidisciplinary management to optimize patient outcomes.

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Publication Details

Journal
Reports — Medical Cases Images and Videos
Published
2025-04-23
DOI
https://doi.org/10.3390/reports8020055
Primary Topic
Infectious Diseases and Tuberculosis
Type
article
Field-Weighted Citation Impact
0.00

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article

Caudate Head Ischemic Stroke with Concurrent Tubercular Meningoencephalitis: A Case Report

Giovanni Fabbrini, Giulia Ruocco, Maria Rosa Ciardi, Matteo Bologna et al.
Reports — Medical Cases Images and Videos
Infectious Diseases and Tuberculosis
article

Caudate Head Ischemic Stroke with Concurrent Tubercular Meningoencephalitis: A Case Report

Giovanni Fabbrini, Giulia Ruocco, Maria Rosa Ciardi, Matteo Bologna, Patrizia Pasculli, Filippo Nuti
article en

Abstract

<b>Background and Clinical Significance</b>: The pathogenesis of ischemic lesions in tubercular meningoencephalitis remains unclear, as do the best therapeutic strategies during the acute phase and for secondary prevention. <b>Case Presentation</b>: We report on an atypical case of tubercular meningoencephalitis with a concomitant ischemic stroke. The infectious origin of the ischemic lesion was hypothesized due to a discrepancy between clinical and radiological findings. The patient underwent neuroimaging, blood tests, and a lumbar puncture to diagnose tubercular meningoencephalitis. She subsequently started on antitubercular therapy. Despite the initiation of treatment, her neurological condition worsened. A computed tomography revealed hydrocephalus, leading to the placement of an external ventricular shunt. This intervention resulted in a reduction in ventricular size and an overall improvement in her clinical condition. To reduce the risk of death, secondary prophylaxis with cardioaspirin was added to her treatment regimen. <b>Conclusions</b>: This report highlights the diagnostic and therapeutic challenges encountered in managing patients with tubercular meningitis presenting with concomitant ischemic stroke. By elucidating the complexities of this clinical scenario, we emphasize the importance of early recognition, comprehensive evaluation, and multidisciplinary management to optimize patient outcomes.

Reports — Medical Cases Images and VideosVol. 8(2)
Istituto Neurologico Mediterraneo (IT), Sapienza University of Rome (IT)
Ministero della Salute
Good health and well-being
Openalex Percentile: Top 86%
Infectious Diseases and Tuberculosis
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