The expression of PRMT5 is associated with postoperative chemotherapeutic outcome in colon cancer
This study highlights PRMT5 as a prognostic marker for adjuvant chemotherapy in patients with colon cancer. The findings suggest that PRMT5 expression may serve as an important predictor of therapeutic outcomes, providing valuable insights for clinical decision-making and personalized treatment strategies.
Authors
- Yuling Sheng
- Changzheng Du (ORCID: https://orcid.org/0000-0001-9016-4401)
- Hongfang Yin
- Yanyun Chang
- Feng Wang
- Huan Li (ORCID: https://orcid.org/0000-0001-5125-069X)
- Qi Liu (ORCID: https://orcid.org/0000-0003-2578-1221)
- Yifan Peng (ORCID: https://orcid.org/0000-0003-0620-3610)
- Xiaowen Sun
- Lu Lü (ORCID: https://orcid.org/0000-0002-8290-8834)
Institutions
- Southern University of Science and Technology (CN)
- Beijing Tsinghua Chang Gung Hospital (CN)
Publication Details
- Journal
- BMC Cancer
- Published
- 2025-04-23
- DOI
- https://doi.org/10.1186/s12885-025-14161-5
- Primary Topic
- Cancer-related gene regulation
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Southern University of Science and Technology