Growth characteristics of children with 21-hydroxylase deficiency and the value of steroid hormones in height assessment
21OHD children exhibit accelerated bone maturation as early as childhood, worsening during adolescence, leading to severely impaired growth potential and final height. 17OHP, 21DOF, and 11-oxy-androgens are promising biomarkers for evaluating growth and bone maturity.
Authors
- Hemeng Chong
- Yalei Pi (ORCID: https://orcid.org/0000-0001-5401-6372)
- Yanan Zhang (ORCID: https://orcid.org/0000-0002-2711-6551)
- Yuqian Li (ORCID: https://orcid.org/0000-0003-4809-052X)
- Yutong Xing
- Huifeng Zhang
Institutions
- Hebei Medical University (CN)
- Second Hospital of Hebei Medical University (CN)
Publication Details
- Journal
- BMC Pediatrics
- Published
- 2025-04-23
- DOI
- https://doi.org/10.1186/s12887-025-05643-3
- Primary Topic
- Sexual Differentiation and Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00