In Vitro Study on the Antitumor Bioactivity of Anderson-Type Polyoxometalates
Novel Anderson-type POMs B1 (vanadium-centered, methyl-modified) and B7 (vanadiumcentered, hydroxyl-modified) exhibited superior efficacy against tumor cells and induced apoptosis via PI3K/ AKT pathway, which provides new theoretical avenues for developing POM-mediated antitumor chemotherapeutic medications.
Authors
- J Y Liu
- Yanhong Wei (ORCID: https://orcid.org/0000-0001-5348-5476)
- Chenguang Yao
- Hanluo Li (ORCID: https://orcid.org/0000-0001-9109-2972)
- Junbin Yan (ORCID: https://orcid.org/0000-0001-5014-7156)
- Kanghong Hu (ORCID: https://orcid.org/0000-0002-5913-2767)
- B. Zhao (ORCID: https://orcid.org/0000-0002-4448-2115)
- Ting Tan (ORCID: https://orcid.org/0000-0002-8685-4837)
- Junjie Wang (ORCID: https://orcid.org/0000-0002-7145-5702)
- William Wang (ORCID: https://orcid.org/0009-0002-6485-9714)
- Romina Onintsoa Diarimalala
Institutions
- Grinnell College (US)
- Second Hospital of Yichang (CN)
- Hubei University of Technology (CN)
Publication Details
- Journal
- Current Pharmaceutical Design
- Published
- 2025-04-23
- DOI
- https://doi.org/10.2174/0113816128367617250323075703
- Citations
- 1
- Primary Topic
- Polyoxometalates: Synthesis and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.52