Long-term impact of anthracycline in early-stage breast cancer, bridging of MiRNAs profiler for early cardiotoxicity
Our study demonstrates a very low incidence of long-term symptomatic CTRCD. The diverse expression patterns of miR-16-5p and miR-1-3p at different time points also provide valuable biological insights. Within-normal results of an exact and comprehensive CMR, in asymptomatic and any LVEF change participants, indicate the long-term safety of limited-dose anthracycline-containing use.
Authors
- Shanop Shuangshoti (ORCID: https://orcid.org/0000-0003-3416-337X)
- Yongkasem Vorasettakarnkij (ORCID: https://orcid.org/0000-0003-0932-731X)
- Piyada Sitthideatphaiboon (ORCID: https://orcid.org/0000-0003-2098-1646)
- Sopark Manasnayakorn (ORCID: https://orcid.org/0000-0002-8145-9555)
- Chatchawit Aporntewan (ORCID: https://orcid.org/0000-0001-7290-8286)
- Nonthikorn Theerasuwipakorn (ORCID: https://orcid.org/0000-0002-3521-7715)
- Chanida Vinayanuwattikun (ORCID: https://orcid.org/0000-0003-3622-7752)
- Nattaya Poovorawan (ORCID: https://orcid.org/0000-0002-5784-1885)
- Pairoj Chattranukulchai (ORCID: https://orcid.org/0000-0001-6153-8398)
- Virote Sriuranpong (ORCID: https://orcid.org/0000-0001-8787-5026)
- Chinachote Teerapakpinyo (ORCID: https://orcid.org/0000-0002-6949-4198)
- Pajaree Chariyavilaskul (ORCID: https://orcid.org/0000-0003-1096-6020)
- Monravee Tumkosit (ORCID: https://orcid.org/0000-0002-8307-1191)
- Thiti Susiriwatananont (ORCID: https://orcid.org/0000-0001-6916-3383)
- Luxica Jarutasnangkul
Institutions
- Chulalongkorn University (TH)
- King Chulalongkorn Memorial Hospital (TH)
Publication Details
- Journal
- Cardio-Oncology
- Published
- 2025-04-23
- DOI
- https://doi.org/10.1186/s40959-025-00337-2
- Citations
- 4
- Primary Topic
- Chemotherapy-induced cardiotoxicity and mitigation
- Type
- article
- Field-Weighted Citation Impact
- 5.55
Funders
- GlaxoSmithKline
- Chulalongkorn University
- Faculty of Medicine, Chulalongkorn University