Structure-based Virtual Screening and Hit Identification of Novel designed Quinazolin-4(3H)-one Derivatives as Antitubercular Agent against Targets Polyketide Synthase 13 and DNA gyrase of Mycobacterium tuberculosis
The results indicated that RBSI64 could be a useful template for developing MDR and XDR-TB inhibitors. The current study contributes to the identification of promising antitubercular candidates against targeted enzymes.
Authors
- P. Sowmiya (ORCID: https://orcid.org/0000-0002-9519-5570)
- G. Revathi (ORCID: https://orcid.org/0000-0001-9419-2637)
- K. Girija
Institutions
- Pondicherry University (IN)
- Research Institute of Health Sciences (ES)
Publication Details
- Journal
- Current Drug Discovery Technologies
- Published
- 2025-04-23
- DOI
- https://doi.org/10.2174/0115701638362095250402180030
- Citations
- 1
- Primary Topic
- Quinazolinone synthesis and applications
- Type
- article
- Field-Weighted Citation Impact
- 0.94