Sex-specific response to A1BG loss results in female dilated cardiomyopathy
A1BG is essential for maintaining ventricular structural integrity in female, but not male, hearts, leading to a chronic remodeling consistent with early-stage DCM.
Authors
- Frank L. Conlon (ORCID: https://orcid.org/0000-0002-5027-0397)
- James I. Emerson (ORCID: https://orcid.org/0000-0002-3281-1655)
- Wei Shi (ORCID: https://orcid.org/0000-0002-8177-2920)
Institutions
- University of North Carolina at Chapel Hill (US)
- University of Nebraska Medical Center (US)
Publication Details
- Journal
- Biology of Sex Differences
- Published
- 2025-04-23
- DOI
- https://doi.org/10.1186/s13293-025-00713-8
- Primary Topic
- Cardiomyopathy and Myosin Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Heart, Lung, and Blood Institute
- Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill