Clinical characteristics, diagnostic challenges, and outcome of paroxysmal sympathetic hyperactivity in pediatric patients: a retrospective cohort study in a tertiary hospital setting
PSH in pediatric patients predominantly arises from non-traumatic brain injuries, presenting with nonspecific symptoms that often lead to misdiagnosis. This study underscores the importance of early and accurate diagnosis in improving patient outcomes. Clonidine shows potential as a life-saving intervention in this context. These findings highlight the need for further research to refine diagnostic criteria and optimize treatment strategies for pediatric PSH.
Authors
- Duaa Baarmah (ORCID: https://orcid.org/0000-0001-6166-5020)
- Wesam Althaqafi (ORCID: https://orcid.org/0009-0007-6837-733X)
- Waad Bader Almanie
- Sulaiman Dakhel Almasoud (ORCID: https://orcid.org/0000-0003-4776-2187)
Institutions
- Princess Nourah bint Abdulrahman University (SA)
- King Saud bin Abdulaziz University for Health Sciences (SA)
- King Saud University (SA)
- King Abdullah International Medical Research Center (SA)
- National Guard Health Affairs (SA)
Publication Details
- Journal
- BMC Neurology
- Published
- 2025-04-23
- DOI
- https://doi.org/10.1186/s12883-025-04163-y
- Primary Topic
- Cardiovascular Syncope and Autonomic Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00