Isolated Uhthoff phenomenon as first manifestation of multiple sclerosis: a case report
This case underscores the importance of recognizing UP as a potential early indicator of MS. Specific diagnostic tools, such as OCT, VEP, and MRI, can be used to objectify optic nerve involvement and should be considered to identify underlying demyelinating conditions. Early diagnosis of MS can facilitate a timely initiation of therapies and improve patient outcomes. It is essential for clinicians to consider UP for better clinical management of MS.
Authors
- Charlotte Bereuter (ORCID: https://orcid.org/0009-0004-7172-8864)
- Judith Bellmann–Strobl (ORCID: https://orcid.org/0000-0003-2615-1643)
- Frederike Cosima Oertel (ORCID: https://orcid.org/0000-0003-4906-5983)
- Murat Delikaya (ORCID: https://orcid.org/0000-0001-5494-8073)
- Annabelle Löffler
Institutions
- Max Delbrück Center (DE)
- Humboldt-Universität zu Berlin (DE)
- Freie Universität Berlin (DE)
- Charité - Universitätsmedizin Berlin (DE)
Publication Details
- Journal
- BMC Neurology
- Published
- 2025-04-23
- DOI
- https://doi.org/10.1186/s12883-025-04193-6
- Citations
- 2
- Primary Topic
- Multiple Sclerosis Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 2.94
Funders
- Charité – Universitätsmedizin Berlin