Host‐Microbial Cometabolite Ursodeoxycholic Acid Protects Against Poststroke Cognitive Impairment
Our findings indicate that UDCA has potential as a biomarker for predicting PSCI risk and plays a neuroprotective role in the progression of PSCI. This suggests that early identification and intervention targeting UDCA could represent a promising strategy for the prevention and treatment of PSCI.
Authors
- Yueran Ren (ORCID: https://orcid.org/0009-0008-8121-3142)
- Y. Deng
- Yu Ma (ORCID: https://orcid.org/0000-0003-2175-3346)
- Boxin Zhao (ORCID: https://orcid.org/0000-0003-3574-0511)
- Huidi Wang (ORCID: https://orcid.org/0009-0003-9727-295X)
- Yan He (ORCID: https://orcid.org/0000-0002-6611-2959)
- Feng Zhang (ORCID: https://orcid.org/0000-0003-3150-1249)
- Jia Yin (ORCID: https://orcid.org/0000-0001-8944-6604)
- Jiafeng Zhang (ORCID: https://orcid.org/0000-0002-3883-548X)
- J. Chen (ORCID: https://orcid.org/0000-0002-9760-012X)
- Xuxuan Gao (ORCID: https://orcid.org/0009-0007-5558-7012)
Institutions
- Ministry of Education of the People's Republic of China (CN)
- Nanfang Hospital (CN)
- Southern Medical University (CN)
- Zhejiang University (CN)
Publication Details
- Journal
- Journal of the American Heart Association
- Published
- 2025-04-23
- DOI
- https://doi.org/10.1161/jaha.124.038862
- Citations
- 2
- Primary Topic
- Diet and metabolism studies
- Type
- article
- Field-Weighted Citation Impact
- 2.33