Evaluating Microglial Dysfunction and Psychiatric Illness by Exploring the Inflammatory Basis of Schizophrenia and Depression in Cross-Sectional Study settings
Peripheral inflammatory markers were seen to be associated with psychiatric symptom severity, which supported the inflammatory hypothesis of mental illness. These cytokines might serve as accessible biomarkers. However, direct microglial assessment and longitudinal studies were needed for confirmation of results.
Authors
- Muhammad Haseeb (ORCID: https://orcid.org/0000-0003-2208-5984)
- Shahid Hussain (ORCID: https://orcid.org/0000-0003-4826-3339)
- Anil Kumar Wadhwani
- Mukamil Shah (ORCID: https://orcid.org/0000-0002-7000-5865)
- Fahad Ul Zain
- Saifullah Mahar
- Syed Muhammad Shahkar Ali
- Noor-E-Hira Memon
Institutions
- Memorial Medical Center (US)
- Shaikh Zayed Hospital (PK)
- Jinnah Sindh Medical University (PK)
- Dow University of Health Sciences (PK)
- Universitas Muhammadiyah Jember (ID)
- Black Country Partnership NHS Foundation Trust (GB)
- The Royal Wolverhampton NHS Trust (GB)
- Quaid-e-Awam University of Engineering, Science and Technology (PK)
Publication Details
- Journal
- Cureus
- Published
- 2025-04-23
- DOI
- https://doi.org/10.7759/cureus.82831
- Primary Topic
- Neuroinflammation and Neurodegeneration Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00