Genomic comparative analysis of Enterobacter asburiae harbouring a conjugative blaIMI−6-plasmid isolated from a public garden in Switzerland
Ambler class A IMI enzymes are minor carbapenemases primarily associated with the Enterobacter cloacae complex. Screening soil surfaces of a well-visited public garden revealed an IMI-6-producing Enterobacter asburiae ST657 near a trash can. The strain harboured a 163-kb conjugative IncFII(Yp) plasmid containing bla<sub>IMI-6</sub> and putative virulence genes. WGS comparative analysis with other clinical and non-clinical E. asburiae ST657 showed that it was genetically related to strains from a patient in France (62 ΔSNPs) and from retail salad in Switzerland (79 ΔSNPs). This finding suggests possible trans-sectoral dissemination of IMI-producing bacteria raising concerns since they could further spread into the community.
Authors
- Andrea Endimiani (ORCID: https://orcid.org/0000-0003-3186-5421)
- Vincent Perreten (ORCID: https://orcid.org/0000-0001-5722-9445)
- Yvonne Spahr
Institutions
- University of Bern (CH)
Publication Details
- Journal
- European Journal of Clinical Microbiology & Infectious Diseases
- Published
- 2025-04-23
- DOI
- https://doi.org/10.1007/s10096-025-05131-7
- Citations
- 2
- Primary Topic
- Antibiotic Resistance in Bacteria
- Type
- article
- Field-Weighted Citation Impact
- 1.18
Funders
- University of Bern
- Institute of Veterinary Bacteriology, University of Bern