Risks of empiric glucocorticoid administration in elderly patients with inflammation of unknown origin: A case report

This case demonstrates that GC therapy in elderly IUO patients can lead to severe complications, including VTE, and delayed malignancy diagnosis. Thorough malignancy and thrombus screening should be conducted before GC initiation. Additionally, when VTE occurs in IUO patients, malignancy should be reassessed, even if other risk factors are present. This case underscores the importance of caution when considering empirical GC therapy for IUO.