Cigarette smoking is associated with levels of the serotonin transporter in the brain: a [11C]DASB PET Study

This study provides the first in vivo evidence that current smoking may be associated with elevated hippocampal SERT binding-possibly reflecting lower synaptic serotonin concentrations, and that this change may normalize following smoking cessation.

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Publication Details

Journal
The International Journal of Neuropsychopharmacology
Published
2025-04-21
DOI
https://doi.org/10.1093/ijnp/pyaf026
Primary Topic
Medical Imaging Techniques and Applications
Type
article
Field-Weighted Citation Impact
0.00

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article

Cigarette smoking is associated with levels of the serotonin transporter in the brain: a [11C]DASB PET Study

Gitte M. Knudsen, Vibe G. Frøkjær, Paul Faulkner, David Erritzøe
The International Journal of Neuropsychopharmacology
Medical Imaging Techniques and Applications
article

Cigarette smoking is associated with levels of the serotonin transporter in the brain: a [11C]DASB PET Study

Gitte M. Knudsen, Vibe G. Frøkjær, Paul Faulkner, David Erritzøe
article en

Abstract

This study provides the first in vivo evidence that current smoking may be associated with elevated hippocampal SERT binding-possibly reflecting lower synaptic serotonin concentrations, and that this change may normalize following smoking cessation.

The International Journal of NeuropsychopharmacologyVol. 28(5)
University of Copenhagen (DK), Queen Mary University of London (GB), Copenhagen University Hospital (DK), Rigshospitalet (DK), Imperial College London (GB)
Lundbeckfonden, Novo Nordisk, H. Lundbeck A/S
Openalex Percentile: Top 87%
Medical Imaging Techniques and Applications
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Cigarette smoking is associated with levels of the serotonin transporter in the brain: a [11C]DASB PET Study — Gitte M. Knudsen, Vibe G. Frøkjær, et al. · The International Journal of Neuropsychopharmacology (2025) | TGRS Research Map | TGRS