Global burden of peripheral arterial disease (1990–2021), global burden trends and the impact of blood lead on peripheral arterial disease: a multidimensional analysis based on NHANES, GBD, and Mendelian randomization
Environmental lead exposure is significantly associated with increased PAD risk, with notable differences in population susceptibility. These findings underscore the necessity of environmental exposure control and tailored prevention strategies to enhance cardiovascular health worldwide.
Authors
- Jinjiao Li (ORCID: https://orcid.org/0000-0002-6961-2756)
- Hua Wei (ORCID: https://orcid.org/0000-0003-4341-8290)
- Congzhi Yan (ORCID: https://orcid.org/0000-0002-9373-0015)
- Xinyu Xu (ORCID: https://orcid.org/0000-0002-1730-1462)
- Jiahao Chen (ORCID: https://orcid.org/0000-0001-7719-3216)
Institutions
- Huaqiao University (CN)
- Wenzhou Medical University (CN)
- First Affiliated Hospital of Wenzhou Medical University (CN)
- Affiliated Hospital of Taishan Medical University (CN)
- Northern Jiangsu People's Hospital (CN)
- Shandong First Medical University (CN)
Publication Details
- Journal
- Journal of Translational Medicine
- Published
- 2025-04-23
- DOI
- https://doi.org/10.1186/s12967-025-06408-3
- Citations
- 8
- Primary Topic
- Peripheral Artery Disease Management
- Type
- article
- Field-Weighted Citation Impact
- 16.05