P2X7 receptor promotes the growth and metastasis of gastric cancer by activating P13/AKT/GSK-3 beta signaling (experimental research)
Our conclusion is that activation of P2X7R promotes the proliferation, metastasis and EMT of GC cells by activating P13/AKT/GSK-3beta signaling, and indicates that P2X7R may become a new potential target for GC treatment.
Authors
- Yongsheng Xu (ORCID: https://orcid.org/0000-0002-5064-9284)
- Chao Huang (ORCID: https://orcid.org/0000-0002-3627-7218)
- Wenlong Wang (ORCID: https://orcid.org/0000-0003-1669-613X)
- Wenjun Zhang
- Hongliang Luo (ORCID: https://orcid.org/0000-0001-9522-8881)
- Jipeng Liu (ORCID: https://orcid.org/0000-0002-0431-2699)
Institutions
- Nanchang University (CN)
- Second Affiliated Hospital of Nanchang University (CN)
Publication Details
- Journal
- International Journal of Surgery
- Published
- 2025-04-22
- DOI
- https://doi.org/10.1097/js9.0000000000002406
- Citations
- 7
- Primary Topic
- Adenosine and Purinergic Signaling
- Type
- article
- Field-Weighted Citation Impact
- 7.82