Thromboelastography for optimizing the diagnosis and management of abnormal uterine bleeding
A comprehensive literature review was conducted on the use of thromboelastography in the diagnosis and treatment of abnormal uterine bleeding. Thromboelastography is a highly informative method for assessing blood coagulation properties, enabling a detailed analysis of all stages of hemostasis, including clot formation dynamics, clot strength, and the efficiency of fibrinolytic processes, thereby providing a comprehensive evaluation of the coagulation system. During and after the COVID-19 pandemic, the importance of thromboelastography has increased significantly as it facilitates the detection of hypercoagulable states, which is critical for patients at high risk of thrombosis. Despite the limited use of thromboelastography in routine clinical practice, its potential in the diagnosis and monitoring of coagulopathies, particularly in conditions of increased thrombosis, makes this method a valuable addition to traditional coagulation tests. The use of thromboelastography enhances the diagnostic capabilities in abnormal uterine bleeding by not only identifying coagulation abnormalities, but also differentiating their underlying pathophysiological mechanisms. This is particularly important in cases where standard diagnostic and therapeutic approaches prove ineffective, as well as in patients with combined coagulopathies who require a personalized treatment strategy.
Authors
- A.Yu. Kurmangaleeva (ORCID: https://orcid.org/0000-0002-2348-1607)
- Irina V. Karachentsova (ORCID: https://orcid.org/0000-0002-0254-690X)
- E. V. Sibirskaya (ORCID: https://orcid.org/0000-0002-4540-6341)
Institutions
- Pirogov Russian National Research Medical University (RU)
- Russian Children's Clinical Hospital (RU)
- City Clinical Hospital (RU)
Publication Details
- Journal
- Journal of obstetrics and women s diseases
- Published
- 2025-04-22
- DOI
- https://doi.org/10.17816/jowd634742
- Primary Topic
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Type
- article
- Field-Weighted Citation Impact
- 0.00