Efficacy of pro‐haemostatic agents in the management of factor Xa inhibitor‐associated intracranial haemorrhages

Patients who presented with intracranial haemorrhages in the presence of clinically significant direct oral anticoagulant levels had a higher risk of mortality that does not appear to change with the use of prohaemostatic agents. The efficacy of prohaemostatic agents may not be as clinically significant based on real-world experience in contrast to previously reported studies.

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Publication Details

Journal
Internal Medicine Journal
Published
2025-04-23
DOI
https://doi.org/10.1111/imj.70074
Primary Topic
Atrial Fibrillation Management and Outcomes
Type
article
Field-Weighted Citation Impact
0.00

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article

Efficacy of pro‐haemostatic agents in the management of factor Xa inhibitor‐associated intracranial haemorrhages

Danny Hsu, Diem Thi Nguyen, Zhiwei Wang, Sara Ng et al.
Internal Medicine Journal
Atrial Fibrillation Management and Outcomes
article

Efficacy of pro‐haemostatic agents in the management of factor Xa inhibitor‐associated intracranial haemorrhages

Danny Hsu, Diem Thi Nguyen, Zhiwei Wang, Sara Ng, Homa Noori
article en

Abstract

Patients who presented with intracranial haemorrhages in the presence of clinically significant direct oral anticoagulant levels had a higher risk of mortality that does not appear to change with the use of prohaemostatic agents. The efficacy of prohaemostatic agents may not be as clinically significant based on real-world experience in contrast to previously reported studies.

Internal Medicine JournalVol. 55(7)
Liverpool Hospital (AU), UNSW Sydney (AU), South Western Sydney Local Health District (AU)
Bristol-Myers Squibb, Pfizer, AstraZeneca, University of New South Wales, Novo Nordisk
Good health and well-being
Openalex Percentile: Top 86%
Atrial Fibrillation Management and Outcomes
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