<b>A</b><b> Narrative Review </b><b>o</b><b>f Prevalence </b><b>o</b><b>f Her</b><sub><b>2</b></sub><b> Positive Invasive </b><b>a</b
Breast cancer is a prevalent malignancy in women globally, with the HER2-positive subtype exhibiting aggressive characteristics. This review examines the prevalence of HER2-positive breast cancer, focusing on both invasive and non-invasive forms. HER2, a transmembrane tyrosine kinase receptor, is overexpressed in a significant subset of breast cancers, influencing tumor behavior and prognosis. The review also explores the impact of HER2 status on disease progression and the effectiveness of current therapeutic strategies. Understanding the prevalence of HER2-positive breast cancer is crucial for tailoring effective treatments and improving patient outcomes.
Authors
- Rafaqet Ali (ORCID: https://orcid.org/0000-0002-3700-457X)
- S. Jabeen (ORCID: https://orcid.org/0000-0002-0155-7383)
- Sadaf Ahmed
- M A Baig (ORCID: https://orcid.org/0000-0002-5151-3354)
- Dua Zhaira
- Zeeshan Raja
- Roshan Afshan
- Muhammad Ahtsham
- Ayesha Kashif
- Nadia Gulzar
Institutions
- University of Sargodha (PK)
- Wayne State University (US)
- Iqra University (PK)
- Riphah International University (PK)
- Pakistan Institute of Medical Sciences (PK)
- Bahria University (PK)
Publication Details
- Journal
- Review journal of neurological & medical sciences review.
- Published
- 2025-04-23
- DOI
- https://doi.org/10.62019/kw5f4656
- Primary Topic
- BRCA gene mutations in cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.00