Onset of vitiligo following contact dermatitis from eyeliner application in a 20-year-old female
Vitiligo is an autoimmune condition characterized by the destruction of melanocytes, leading to depigmented skin patches. Allergic contact dermatitis, triggered by allergens in cosmetics, can initiate localized immune responses that may progress to systemic immune dysregulation in genetically predisposed individuals. This case explores the potential role of allergic contact dermatitis in triggering vitiligo and proposes mechanisms underlying this association.
Authors
- Caterina Mariarosaria Giorgio (ORCID: https://orcid.org/0009-0003-2148-8914)
- Eugenia Veronica Di Brizzi (ORCID: https://orcid.org/0000-0002-0278-2443)
- Gaetano Licata (ORCID: https://orcid.org/0000-0002-0834-1331)
- Giuseppe Argenziano (ORCID: https://orcid.org/0000-0003-1413-8214)
- Nicola Maria Giorgio
Institutions
- University of Campania "Luigi Vanvitelli" (IT)
- Ospedale Sant Antonio (IT)
- University of Campania "Luigi Vanvitelli" (IT)
Publication Details
- Journal
- Dermatology Reports
- Published
- 2025-04-23
- DOI
- https://doi.org/10.4081/dr.2025.10220
- Primary Topic
- melanin and skin pigmentation
- Type
- article
- Field-Weighted Citation Impact
- 0.00