Vaccines Matter: Measles and Its Complications

When I was seven, my eldest brother, Sammy, was diagnosed with subacute sclerosing panencephalitis (SSPE) - a sequela of measles infection. He rapidly deteriorated into a vegetative state. Looking back, the bulk of my childhood consisted of mixing nasogastric feeds for him and assisting with his physical therapy alongside my grandfather to prevent worsening contractures. It was extremely traumatic, to say the least. Watching my own brother gradually lose his ability to speak, seeing his lifeless, glassy doll eyes, and witnessing his body become an empty vessel was devastating. He eventually became so cachectic that his bones and joints were accentuated. His body deteriorated, fingers fixed in constant flexion, and his limbs ridden with contractures. Sammy ultimately passed away when I was 17, after living for 10 years with SSPE.

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Publication Details

Journal
PEDIATRICS
Published
2025-04-21
DOI
https://doi.org/10.1542/peds.2025-071622
Citations
2
Primary Topic
Virology and Viral Diseases
Type
article
Field-Weighted Citation Impact
2.71
Controls
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article

Vaccines Matter: Measles and Its Complications

Christopher Kuo
2 citations
PEDIATRICS
Virology and Viral Diseases
2.71
article

Vaccines Matter: Measles and Its Complications

Christopher Kuo
article en
2 citations

Abstract

When I was seven, my eldest brother, Sammy, was diagnosed with subacute sclerosing panencephalitis (SSPE) - a sequela of measles infection. He rapidly deteriorated into a vegetative state. Looking back, the bulk of my childhood consisted of mixing nasogastric feeds for him and assisting with his physical therapy alongside my grandfather to prevent worsening contractures. It was extremely traumatic, to say the least. Watching my own brother gradually lose his ability to speak, seeing his lifeless, glassy doll eyes, and witnessing his body become an empty vessel was devastating. He eventually became so cachectic that his bones and joints were accentuated. His body deteriorated, fingers fixed in constant flexion, and his limbs ridden with contractures. Sammy ultimately passed away when I was 17, after living for 10 years with SSPE.

PEDIATRICSVol. 156(1)
University of Southern California (US), Children's Hospital of Los Angeles (US)
Good health and well-being
Openalex Percentile: Top 11%
Virology and Viral Diseases
2.71
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Vaccines Matter: Measles and Its Complications — Christopher Kuo · PEDIATRICS (2025) | TGRS Research Map | TGRS