Hypothyroidism phenotypes, clinical characteristics, and factors associated with nodular thyroid disease in patients with hypothyroidism in Southern Ghana: a 6-year retrospective study

Our results provide insight into the frequency of hypothyroidism phenotypes, clinical characteristics, and factors associated with nodular thyroid, emphasizing male gender as an independent predictor of nodular thyroid disease. Our findings also emphasize the need for lifestyle adjustment as a mitigating strategy in the management of hypothyroidism. However, prospective studies are required to confirm the findings or investigate the histological characteristics of thyroid nodules in patients with hypothyroidism.

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Publication Details

Journal
BMC Endocrine Disorders
Published
2025-04-21
DOI
https://doi.org/10.1186/s12902-025-01934-z
Primary Topic
Thyroid Disorders and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Hypothyroidism phenotypes, clinical characteristics, and factors associated with nodular thyroid disease in patients with hypothyroidism in Southern Ghana: a 6-year retrospective study

Christian Obirikorang, Samuel Ametepe, E Nyarko, Precious Kwablah Kwadzokpui et al.
BMC Endocrine Disorders
Thyroid Disorders and Treatments
article

Hypothyroidism phenotypes, clinical characteristics, and factors associated with nodular thyroid disease in patients with hypothyroidism in Southern Ghana: a 6-year retrospective study

Christian Obirikorang, Samuel Ametepe, E Nyarko, Precious Kwablah Kwadzokpui, James Osei-Yeboah, Sylvester Yao Lokpo, Alaa Ibrahim, Michael Appiah, Esther Ngozi Adejumo, Belinda Ampomah Kwarteng, Brian Yaw Entsiey Nyarko, Isaac Wormekpor, Bright Kantah
article en

Abstract

Our results provide insight into the frequency of hypothyroidism phenotypes, clinical characteristics, and factors associated with nodular thyroid, emphasizing male gender as an independent predictor of nodular thyroid disease. Our findings also emphasize the need for lifestyle adjustment as a mitigating strategy in the management of hypothyroidism. However, prospective studies are required to confirm the findings or investigate the histological characteristics of thyroid nodules in patients with hypothyroidism.

BMC Endocrine DisordersVol. 25(1)
Ministry of Health (GH), University of Ghana (GH), Accra Technical University (GH), University of Health and Allied Sciences (GH), Kwame Nkrumah University of Science and Technology (GH), Babcock University (NG), Koforidua Technical University (GH)
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Openalex Percentile: Top 89%
Thyroid Disorders and Treatments
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Hypothyroidism phenotypes, clinical characteristics, and factors associated with nodular thyroid disease in patients with hypothyroidism in Southern Ghana: a 6-year retrospective study — Christian Obirikorang, Samuel Ametepe, et al. · BMC Endocrine Disorders (2025) | TGRS Research Map | TGRS