Associations between type III interferons, obesity and clinical severity of COVID-19
These data reveal an important role for IFNλ2 as an immune correlate that predicts COVID-19 disease severity, which may be masked in those with obesity.
Authors
- Riya Negi (ORCID: https://orcid.org/0000-0003-3098-2933)
- Gurvin Saini (ORCID: https://orcid.org/0000-0002-1746-4579)
- Gabriel González (ORCID: https://orcid.org/0000-0002-2180-2120)
- Christine Kelly (ORCID: https://orcid.org/0000-0002-3239-7714)
- Alan Landay (ORCID: https://orcid.org/0000-0001-9645-1356)
- Patrick Mallon (ORCID: https://orcid.org/0000-0002-4337-6222)
- Mary M. Horgan (ORCID: https://orcid.org/0000-0003-0288-4455)
- Eoin R. Feeney (ORCID: https://orcid.org/0000-0003-4118-4945)
- Corinna Sadlier (ORCID: https://orcid.org/0000-0002-8415-2022)
- Dana Alalwan
- Obada Yousif (ORCID: https://orcid.org/0000-0001-5178-0949)
- Aoife G. Cotter (ORCID: https://orcid.org/0000-0001-7712-3533)
- Eoghan de Barra (ORCID: https://orcid.org/0000-0001-7679-5565)
- Grace Kenny (ORCID: https://orcid.org/0000-0002-9646-7910)
- Michael J. Carr (ORCID: https://orcid.org/0000-0003-0011-6209)
- Colette Gaillard (ORCID: https://orcid.org/0000-0002-7064-2530)
- C. Heckmann
- Alejandro Abner Garcia Leon
Institutions
- University College Dublin (IE)
- Royal College of Surgeons in Ireland (IE)
- Université Côte d'Azur (FR)
- Hokkaido University (JP)
- Wexford General Hospital (IE)
- Beaumont Hospital (IE)
- Cork University Hospital (IE)
- Mater Misericordiae University Hospital (IE)
- Sapporo International University (JP)
- St. Vincent's University Hospital (IE)
- Observatoire de la Côte d’Azur (FR)
- The University of Texas Medical Branch at Galveston (US)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-04-22
- DOI
- https://doi.org/10.3389/fimmu.2025.1516756
- Primary Topic
- COVID-19 Clinical Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Science Foundation Ireland