Abstract 1050: Geographic disparities in the incidence of breast and prostate cancers among African Americans: A comparative analysis between the UChicago and Baylor catchment areas

Abstract Background: Cancer disparities continue to be a significant challenge for public health across the nation, especially among African Americans. Causes include socioeconomic factors, environmental conditions, and limited healthcare access. We are exploring data-driven studies of geographic disparities in the incidence rates for breast and prostate cancers across African American populations in catchment areas around the University of Chicago and Baylor College of Medicine. Methods: Catchment areas were identified using our intelligent Catchment Analysis Tool, or iCAT, to map physical boundaries, referral patterns, distances, and population densities. Data were extracted from the SEER Program, CDC WONDER, and the American Community Survey (ACS). The variables analyzed included cancer incidence rates, demographic and socioeconomic factors, healthcare access and utilization, and environmental exposures, including air pollution and water quality. Chi-square tests, t-tests, logistic regression, and multivariate analysis were also performed to identify key drivers of disparities. The results were displayed on geographic maps, charts, and graphs, highlighting spatial clusters and relationships between cancer incidence and contributing factors. Results: Our preliminary findings indicate large disparities in cancer incidence rates between the two catchment areas. We investigate associations between socioeconomic inequality, healthcare access, and environmental exposures. African Americans living in areas of the lowest socioeconomic status and decreased healthcare access demonstrated higher incidence rates. Conclusions: This study can catalyze a focus on systemic inequity in socioeconomic conditions, healthcare accessibility, and environmental quality that influence cancer disparities among African Americans. These findings suggest actionable insights toward targeted interventions and policymaking within the UChicago and Baylor catchment areas. Citation Format: Ahmed Fadiel, Fadiel A., Fadel S. , Oluyomi A. , Rosales O. , Eichenbaum K.D. , Abbasi M. 1, Elbialy A. , an, kunle Odunsi, Saleh Fadel. Geographic disparities in the incidence of breast and prostate cancers among African Americans: A comparative analysis between the UChicago and Baylor catchment areas [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2025; Part 1 (Regular Abstracts); 2025 Apr 25-30; Chicago, IL. Philadelphia (PA): AACR; Cancer Res 2025;85(8_Suppl_1):Abstract nr 1050.