A case of sustained neurological improvement in a metastatic intramedullary spinal cord tumor from lung cancer treated with immune checkpoint inhibitor therapy

Recent studies have demonstrated the efficacy of immune checkpoint inhibitors for brain metastases of lung cancer with high PD-L1 expression. In our case, spinal cord edema resolved, and the residual tumor regressed, with good neurological function sustained over 2 years. These findings suggest that immune checkpoint inhibitors may also be effective for metastatic intramedullary spinal cord tumors.