Prevention of Abdominal Ventral Hernia Using a Poly-4-Hydroxybutyrate Monofilament Mesh in Patients Undergoing Ventriculoperitoneal Shunt Placement for Hydrocephalus

Background The study aimed to evaluate the efficacy of poly-4-hydroxybutyrate (P4HB) monofilament mesh in preventing abdominal ventral hernia and reducing shunt revisions due to catheter migration in patients undergoing ventriculoperitoneal (VP) shunt surgery for hydrocephalus. Methods This retrospective, single-center study included patients who underwent VP shunt surgery for hydrocephalus between 2017 and 2022. Patients were divided into two groups: Group A (no mesh placement) and Group B (mesh placement using P4HB monofilament mesh for hernia prevention). Data were collected and analyzed to assess the outcomes of hernia prevention and shunt revision rates in both groups. Results Among the 46 patients analyzed, Group B (mesh placement) showed a lower incidence of hernia formation and fewer shunt revisions compared to Group A. BMI and recurrence interval were identified as key predictors of shunt revision, with thresholds of 24.05 kg/m² and 17 months demonstrating high sensitivity and specificity. Conclusions The use of P4HB monofilament mesh in VP shunt surgery effectively reduces hernia formation and shunt revisions. Incorporating this mesh into surgical practice may improve outcomes for patients with hydrocephalus.

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Journal
Cureus
Published
2025-04-21
DOI
https://doi.org/10.7759/cureus.82753
Primary Topic
Cerebrospinal fluid and hydrocephalus
Type
article
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article

Prevention of Abdominal Ventral Hernia Using a Poly-4-Hydroxybutyrate Monofilament Mesh in Patients Undergoing Ventriculoperitoneal Shunt Placement for Hydrocephalus

K Baxevanidou, Charalabos Gatos, George Fotakopoulos, Vasiliki Georgakopoulou et al.
Cureus
Cerebrospinal fluid and hydrocephalus
article

Prevention of Abdominal Ventral Hernia Using a Poly-4-Hydroxybutyrate Monofilament Mesh in Patients Undergoing Ventriculoperitoneal Shunt Placement for Hydrocephalus

K Baxevanidou, Charalabos Gatos, George Fotakopoulos, Vasiliki Georgakopoulou, Konstantinos Eleftherios Koumarelas, Grigorios Christodoulidis
article en

Abstract

Background The study aimed to evaluate the efficacy of poly-4-hydroxybutyrate (P4HB) monofilament mesh in preventing abdominal ventral hernia and reducing shunt revisions due to catheter migration in patients undergoing ventriculoperitoneal (VP) shunt surgery for hydrocephalus. Methods This retrospective, single-center study included patients who underwent VP shunt surgery for hydrocephalus between 2017 and 2022. Patients were divided into two groups: Group A (no mesh placement) and Group B (mesh placement using P4HB monofilament mesh for hernia prevention). Data were collected and analyzed to assess the outcomes of hernia prevention and shunt revision rates in both groups. Results Among the 46 patients analyzed, Group B (mesh placement) showed a lower incidence of hernia formation and fewer shunt revisions compared to Group A. BMI and recurrence interval were identified as key predictors of shunt revision, with thresholds of 24.05 kg/m² and 17 months demonstrating high sensitivity and specificity. Conclusions The use of P4HB monofilament mesh in VP shunt surgery effectively reduces hernia formation and shunt revisions. Incorporating this mesh into surgical practice may improve outcomes for patients with hydrocephalus.

CureusVol. 17(4)
AHEPA University Hospital (GR), University Hospital of Larissa (GR), Laiko General Hospital of Athens (GR)
Openalex Percentile: Top 90%
Cerebrospinal fluid and hydrocephalus
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Prevention of Abdominal Ventral Hernia Using a Poly-4-Hydroxybutyrate Monofilament Mesh in Patients Undergoing Ventriculoperitoneal Shunt Placement for Hydrocephalus — K Baxevanidou, Charalabos Gatos, et al. · Cureus (2025) | TGRS Research Map | TGRS