Adverse reactions of four multi-targeted tyrosine kinase inhibitors: a descriptive analysis of the WHO-VigiAccess database
Recent comparative observational research suggests that the ADR reports submitted to the WHO and the FDA for these medications highlight both common and specific ADRs. It is essential for clinical practitioners to develop personalized treatment strategies that consider the adverse effects linked to different medications, alongside the unique circumstances of their patients, thus encouraging the responsible use of these MTKIs.
Authors
- Xuefan Zeng
- Jiayu Bai (ORCID: https://orcid.org/0000-0003-3336-9464)
- Lijun Li (ORCID: https://orcid.org/0009-0000-4299-7935)
- X. Wen
Institutions
- Jiangnan University (CN)
- Dalian Medical University (CN)
- First Affiliated Hospital of Dalian Medical University (CN)
- Chongqing Medical University (CN)
- University of South China (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2025-04-22
- DOI
- https://doi.org/10.3389/fphar.2025.1585862
- Citations
- 1
- Primary Topic
- Chronic Myeloid Leukemia Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.77