Adverse reactions of four multi-targeted tyrosine kinase inhibitors: a descriptive analysis of the WHO-VigiAccess database

Recent comparative observational research suggests that the ADR reports submitted to the WHO and the FDA for these medications highlight both common and specific ADRs. It is essential for clinical practitioners to develop personalized treatment strategies that consider the adverse effects linked to different medications, alongside the unique circumstances of their patients, thus encouraging the responsible use of these MTKIs.

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Publication Details

Journal
Frontiers in Pharmacology
Published
2025-04-22
DOI
https://doi.org/10.3389/fphar.2025.1585862
Citations
1
Primary Topic
Chronic Myeloid Leukemia Treatments
Type
article
Field-Weighted Citation Impact
1.77
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article

Adverse reactions of four multi-targeted tyrosine kinase inhibitors: a descriptive analysis of the WHO-VigiAccess database

Xuefan Zeng, Jiayu Bai, Lijun Li, X. Wen
1 citations
Frontiers in Pharmacology
Chronic Myeloid Leukemia Treatments
1.77
article

Adverse reactions of four multi-targeted tyrosine kinase inhibitors: a descriptive analysis of the WHO-VigiAccess database

Xuefan Zeng, Jiayu Bai, Lijun Li, X. Wen
article en
1 citations

Abstract

Recent comparative observational research suggests that the ADR reports submitted to the WHO and the FDA for these medications highlight both common and specific ADRs. It is essential for clinical practitioners to develop personalized treatment strategies that consider the adverse effects linked to different medications, alongside the unique circumstances of their patients, thus encouraging the responsible use of these MTKIs.

Frontiers in PharmacologyVol. 16
Jiangnan University (CN), Dalian Medical University (CN), First Affiliated Hospital of Dalian Medical University (CN), Chongqing Medical University (CN), University of South China (CN)
Good health and well-being
Openalex Percentile: Top 17%
Chronic Myeloid Leukemia Treatments
1.77
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