MR-guided focused ultrasound thalamotomy modulates cerebello-thalamo-cortical tremor network in essential tremor patients
Our findings of altered functional connectivity within the cerebello-thalamo-cortical network, encompassing regions involved in motor, sensory, attention, visual, and visuospatial functions, and its association with hand tremor improvement suggest that targeting functional connectivity abnormalities may be a potential approach for alleviating tremor symptoms in ET patients.
Authors
- Elias R. Melhem (ORCID: https://orcid.org/0000-0001-5869-9449)
- Jiachen Zhuo (ORCID: https://orcid.org/0000-0001-6637-701X)
- Howard M. Eisenberg (ORCID: https://orcid.org/0000-0001-5763-1346)
- Andrew J. Furman (ORCID: https://orcid.org/0000-0001-8055-9610)
- Dheeraj Gandhi (ORCID: https://orcid.org/0000-0001-6741-5970)
- Rao P. Gullapalli (ORCID: https://orcid.org/0000-0003-0551-0379)
- Jiang Li (ORCID: https://orcid.org/0000-0001-5596-9159)
- Paul Fishman
Institutions
- University of Maryland, Baltimore (US)
- Advanced Imaging Research (United States) (US)
Publication Details
- Journal
- Frontiers in Neurology
- Published
- 2025-04-22
- DOI
- https://doi.org/10.3389/fneur.2025.1526501
- Primary Topic
- Neurological disorders and treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00