Abstract 3727: Physical activity patters according to demographic, social, and clinical correlates among breast cancer survivors

Abstract INTRODUCTION: Moderate to Vigorous Physical Activity (MVPA) after breast cancer diagnosis is associated with improved survivorship, suggesting the need for interventions to increase MVPA. However, differences in MVPA by race and age among breast cancer survivors are not well described in population-based studies. METHODS: We analyzed data from Carolina Breast Cancer Study Phase 3 (CBCS3, n =2994, 50% Black) participants to evaluate the trajectory of MVPA up to 18-month post-diagnosis. Participants were classified as having Any MVPA (and Sufficient or Insufficient according to national guidelines) or No MVPA. Associations between MVPA and demographic, social, and clinical variables were estimated using multivariable logistic regression. RESULTS: At baseline, 84.0% of participants reported Any MVPA pre-diagnosis, which dropped to 55.4% at 6-month post-diagnosis, then rebounded to 85.1% by 18-month post-diagnosis. Among those who had No MVPA pre-diagnosis, 32.5% and 71.0% became active at 6- and 18-month post-diagnosis, respectively. Race was not significantly associated with Any MVPA [OR =1.12, 95%CI (0.90, 1.39) Non-black vs. Black], but higher income [OR =1.33, 95%CI (1.02, 1.74) >$30K vs. <15K], lower Body Mass Index (BMI) [OR = 1.30, 95%CI (1.00, 1.73) <25 vs. >30], low area deprivation [OR = 1.35, 95%CI(1.08, 1.67) vs. high], high area assets [OR =1.54, 95%CI (1.23, 1.93) vs. low], and stage I [OR = 1.72, 95%CI(1.22, 2.43) vs. 3 or 4], were associated with Any MVPA at 18-month post-diagnosis. CONCLUSION: Individual and community-level socio-economic status (SES) are strong predictors of Any MVPA, and together with established clinical correlates (such as late disease), these factors may contribute to breast cancer disparities. Citation Format: Michael Kebede, Charles E. Matthews, Matthew R. Dunn, Natasha R. Burse, Annie G. Howard, Kelly R. Evenson, Melissa A. Troester. Physical activity patters according to demographic, social, and clinical correlates among breast cancer survivors [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2025; Part 1 (Regular Abstracts); 2025 Apr 25-30; Chicago, IL. Philadelphia (PA): AACR; Cancer Res 2025;85(8_Suppl_1):Abstract nr 3727.