Reference range of neutrophil-to-lymphocyte ratio in healthy individuals and its predictive value for post-trauma nosocomial infections
The current 2.5th-97.5th percentile range of NLR is 0.69-3.48 in minors and 0.86-3.83 in adults. With increasing age, the reference range widens, and females tend to have a slightly broader range than males. NLR is an independent risk factor for post-trauma infections, showing higher predictive value in patients over 60 years of age. Although NLR cannot differentiate infection sites or pathogen types, elevated NLR values may provide a reference for identifying fungal infections.
Authors
- Jingyao Zhang (ORCID: https://orcid.org/0000-0002-2854-5446)
- Rui Li (ORCID: https://orcid.org/0009-0000-8719-0350)
- Lebin Gan (ORCID: https://orcid.org/0000-0002-2357-8943)
- Qiang Wang (ORCID: https://orcid.org/0000-0003-1466-8450)
- Diya Sun (ORCID: https://orcid.org/0000-0001-5253-4571)
- Jingjing Ye (ORCID: https://orcid.org/0009-0000-8906-4454)
- Yufeng Jiang (ORCID: https://orcid.org/0000-0002-1405-7513)
- Tianbing Wang (ORCID: https://orcid.org/0000-0002-5431-0931)
- Mengwei Zhang
- Feifei Jin
- Zishuo Pei (ORCID: https://orcid.org/0009-0003-1514-7013)
Institutions
- Integrated Chinese Medicine (China) (HK)
Publication Details
- Journal
- Frontiers in Cellular and Infection Microbiology
- Published
- 2025-04-22
- DOI
- https://doi.org/10.3389/fcimb.2025.1529532
- Citations
- 4
- Primary Topic
- Inflammatory Biomarkers in Disease Prognosis
- Type
- article
- Field-Weighted Citation Impact
- 4.18
Funders
- National Natural Science Foundation of China
- Peking University
- Peking University People's Hospital