Integrating network pharmacology and experimental validation to investigate the mechanism of Gualou Xiebai Banxia decoction against myocardial ischemia
This study suggested that GXBD alleviates myocardial ischemia by ameliorating mitochondrial dysfunction through the PI3K/AKT/NRF2 signaling pathway.
Authors
- Wenxuan Liu (ORCID: https://orcid.org/0000-0003-1227-0991)
- Ping Shao (ORCID: https://orcid.org/0000-0002-2793-831X)
- Chunmei Dai (ORCID: https://orcid.org/0000-0002-1364-4388)
- Feifei Liu
- Xiaorui Han (ORCID: https://orcid.org/0000-0001-9510-4838)
- Kai Zeng (ORCID: https://orcid.org/0000-0002-9440-2304)
- Wanjun Zhu
- Ren Ying (ORCID: https://orcid.org/0009-0006-5905-0709)
Institutions
- Jinzhou Medical University (CN)
- Praxis (EE)
Publication Details
- Journal
- Frontiers in Cardiovascular Medicine
- Published
- 2025-04-22
- DOI
- https://doi.org/10.3389/fcvm.2025.1512791
- Citations
- 2
- Primary Topic
- Traditional Chinese Medicine Studies
- Type
- article
- Field-Weighted Citation Impact
- 4.76