Posterior Reversible Encephalopathy Syndrome: The Eyes Reflecting Systemic Health

Posterior reversible encephalopathy syndrome (PRES) is a condition marked by reversible subcortical brain swelling, often accompanied by acute neurological symptoms. It is commonly associated with renal failure, blood pressure fluctuations, cytotoxic drugs, autoimmune disorders, and preeclampsia or eclampsia. We report the case of a 34-year-old female who developed sudden blurring of vision in both eyes after an episode of accelerated hypertension. Neurological imaging revealed features of PRES, and fundoscopy showed hypertensive retinopathy in both eyes. She was managed aggressively in the ICU, and her best corrected visual acuity improved after one week, with gradual resolution of the hypertensive retinopathy. PRES typically follows a benign course, with visual deficits often resolving as the underlying systemic condition improves.

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Publication Details

Journal
Cureus
Published
2025-04-21
DOI
https://doi.org/10.7759/cureus.82754
Primary Topic
Neurological Complications and Syndromes
Type
article
Field-Weighted Citation Impact
0.00
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article

Posterior Reversible Encephalopathy Syndrome: The Eyes Reflecting Systemic Health

Vinita Ramnani, Divya Trivedi, Sakshi Ramnani, Rahul Jain et al.
1 links
Cureus
Neurological Complications and Syndromes
article

Posterior Reversible Encephalopathy Syndrome: The Eyes Reflecting Systemic Health

Vinita Ramnani, Divya Trivedi, Sakshi Ramnani, Rahul Jain, Prateek Deo
article en

Abstract

Posterior reversible encephalopathy syndrome (PRES) is a condition marked by reversible subcortical brain swelling, often accompanied by acute neurological symptoms. It is commonly associated with renal failure, blood pressure fluctuations, cytotoxic drugs, autoimmune disorders, and preeclampsia or eclampsia. We report the case of a 34-year-old female who developed sudden blurring of vision in both eyes after an episode of accelerated hypertension. Neurological imaging revealed features of PRES, and fundoscopy showed hypertensive retinopathy in both eyes. She was managed aggressively in the ICU, and her best corrected visual acuity improved after one week, with gradual resolution of the hypertensive retinopathy. PRES typically follows a benign course, with visual deficits often resolving as the underlying systemic condition improves.

CureusVol. 17(4)
Sankara Nethralaya (IN), Indra (Spain) (ES), Bansal Institute Of Research Technology & Science (IN)
Openalex Percentile: Top 89%
Neurological Complications and Syndromes
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