An Injectable Kartogenin-Incorporated Hydrogel Supports Mesenchymal Stem Cells for Cartilage Tissue Engineering
The injectable CMC/DACNC hydrogel, combined with KGN and MSCs, synergistically enhanced cartilage regeneration both in vitro and in vivo. This study highlights the potential of this hydrogel as a promising scaffold for cartilage tissue engineering, offering a novel therapeutic approach for cartilage defects and injuries.
Authors
- Guoqing Zhong (ORCID: https://orcid.org/0000-0002-1242-5327)
- Weijuan Huang (ORCID: https://orcid.org/0000-0002-8655-130X)
- Chongquan Huang (ORCID: https://orcid.org/0000-0002-3571-0155)
- Shi Cheng (ORCID: https://orcid.org/0000-0002-2631-3262)
- Lingyun Chen (ORCID: https://orcid.org/0000-0003-2277-7470)
- Xiaolan Wang (ORCID: https://orcid.org/0000-0002-3549-3680)
- Jin Xiao
- Yu Zhang (ORCID: https://orcid.org/0009-0009-1389-916X)
Institutions
- South China Agricultural University (CN)
- University of Alberta (CA)
- Guangdong Academy of Medical Sciences (CN)
- Guangdong Provincial People's Hospital (CN)
- Southern Medical University (CN)
Publication Details
- Journal
- Bioengineering
- Published
- 2025-04-22
- DOI
- https://doi.org/10.3390/bioengineering12050434
- Citations
- 2
- Primary Topic
- Osteoarthritis Treatment and Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 3.34
Funders
- National Natural Science Foundation of China