Effect of early administration of inhaled heparin on outcomes of smoke inhalation injury: A randomized controlled trial
The early administration of inhaled heparin to patients suffering smoke inhalation injury was associated with more VFDs and enhanced weaning from mechanical ventilation. Inhaled heparin was also associated with more ICU-free days, higher PaO<sub>2</sub>/FiO<sub>2</sub> ratios, and fewer mechanical ventilation days in survivors. Larger randomized controlled trials are required to establish the role of inhaled heparin as a standard of care in this clinical setting.
Authors
- Sameh M. Hakim (ORCID: https://orcid.org/0000-0003-1900-0353)
- Mahmoud Saad Mohamed
- Mohamed M. Fouad (ORCID: https://orcid.org/0000-0001-6382-9199)
- Mariam Kamal Habib
- Safaa Ishak Ghaly
Institutions
- Ain Shams University (EG)
Publication Details
- Journal
- Burns
- Published
- 2025-04-22
- DOI
- https://doi.org/10.1016/j.burns.2025.107518
- Citations
- 1
- Primary Topic
- Respiratory Support and Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 1.52