The single degree of polymerization influences the efficacy of xylooligosaccharides in shaping microbial and metabolite profiles in chicken gut to combat avian pathogenic Escherichia coli
XOS and their major monomers differentially improved gut microbiota and metabolite profiles in chicken gut against APEC challenge. Overall, xylotriose exhibited the greatest inhibition against APEC abundance and virulence. Our findings underscore the role of single DP in influencing the prebiotic actions of XOS against APEC, providing a basis for the reasonable application of XOS in diets to combat bacterial challenge.
Authors
- Fei Yan (ORCID: https://orcid.org/0000-0002-6429-7443)
- Zemin Dong (ORCID: https://orcid.org/0000-0001-5649-6496)
- Zhou Yu-ping (ORCID: https://orcid.org/0009-0002-9727-1730)
- Jianjun Zuo (ORCID: https://orcid.org/0000-0002-5320-5494)
- Lulu Ren (ORCID: https://orcid.org/0000-0003-3891-7992)
- Weiwei Wang (ORCID: https://orcid.org/0000-0002-1886-6748)
- Hui Ye (ORCID: https://orcid.org/0000-0001-9880-7803)
- Changming Zhang (ORCID: https://orcid.org/0000-0002-9703-7955)
- Qingyun Cao (ORCID: https://orcid.org/0000-0002-0821-2097)
- Huiyun Zhou
Institutions
- South China Agricultural University (CN)
Publication Details
- Journal
- BMC Microbiology
- Published
- 2025-04-22
- DOI
- https://doi.org/10.1186/s12866-025-03948-y
- Citations
- 1
- Primary Topic
- Microbial Metabolites in Food Biotechnology
- Type
- article
- Field-Weighted Citation Impact
- 1.12
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Guangdong Province