Novel Approach to Proficiency Testing Reveals Significant Variations in Biomarker Practice Leading to Critical Differences in Lung Cancer Management
This report demonstrates the utility of this proficiency testing style compared with standard laboratory self-reporting. The approach has elucidated substantial differences in the quality of NSCLC biomarker results produced by Canadian laboratories. Ongoing efforts to improve turnaround times and clarity of reporting, including regular external measurement, are tools that can improve patient outcomes in NSCLC.
Authors
- Michael D. Carter (ORCID: https://orcid.org/0000-0003-3964-9790)
- Normand Blais (ORCID: https://orcid.org/0000-0003-2698-4362)
- Stephen Yip (ORCID: https://orcid.org/0000-0002-8514-9861)
- Stephanie Snow (ORCID: https://orcid.org/0000-0003-3847-0289)
- Basile Tessier‐Cloutier (ORCID: https://orcid.org/0000-0001-8739-3879)
- Andrea Beharry
- Bernard Lo (ORCID: https://orcid.org/0000-0001-6210-9667)
- Jennifer Won
- Patrice Desmeules (ORCID: https://orcid.org/0000-0002-1747-6705)
- Parneet Kaur Cheema (ORCID: https://orcid.org/0000-0002-9680-7073)
- Brandon S. Sheffield (ORCID: https://orcid.org/0000-0002-9234-6134)
- Kassandra R. Bisson (ORCID: https://orcid.org/0000-0002-4486-1983)
- Barbara Melosky (ORCID: https://orcid.org/0000-0003-2865-659X)
- John G. Garratt
- Edwin Tio
Institutions
- University of British Columbia (CA)
- Queen Elizabeth II Health Sciences Centre (CA)
- Ottawa Hospital (CA)
- McGill University Health Centre (CA)
- William Osler Health System (CA)
Publication Details
- Journal
- JTO Clinical and Research Reports
- Published
- 2025-04-22
- DOI
- https://doi.org/10.1016/j.jtocrr.2025.100837
- Primary Topic
- Lung Cancer Treatments and Mutations
- Type
- article
- Field-Weighted Citation Impact
- 0.00