B cell–derived exosomal miR-483-5p and its potential role in promoting kidney function loss in IgA nephropathy
Interaction of B lymphocyte-derived miR-enriched exosomes with tubular epithelial cells may provide an explanation for the progressive tubulointerstitial scarring and loss of kidney function seen in IgAN.
Authors
- David Wimbury (ORCID: https://orcid.org/0000-0001-6102-3925)
- Jeremy R. Glissen Brown (ORCID: https://orcid.org/0000-0002-7204-7241)
- Jonathan Barratt (ORCID: https://orcid.org/0000-0002-9063-7229)
- Jasraj S. Bhachu
- Haresh Selvaskandan (ORCID: https://orcid.org/0000-0002-2874-7005)
- Kees R. Straatman (ORCID: https://orcid.org/0000-0002-9812-492X)
- Michael Thoreau Lacey (ORCID: https://orcid.org/0000-0002-4808-6064)
- Chidimma Mbadugha
- Izabella Pawluczyk
Institutions
- University of Leicester (GB)
- Arkana Laboratories (US)
Publication Details
- Journal
- Kidney International
- Published
- 2025-04-22
- DOI
- https://doi.org/10.1016/j.kint.2025.03.019
- Citations
- 5
- Primary Topic
- Extracellular vesicles in disease
- Type
- article
- Field-Weighted Citation Impact
- 4.03
Funders
- Kidney Research UK
- University of Leicester